BioBlox2D is a free mobile game for iOS and Android where you have to dock molecules together! Matching different shapes and charges. Switch, Rotate, Swipe and match the Ligands to create the perfect match for the Receptor. Learn about the fascinating world of bio-molecules and their interactions!
BioBlox3D is a free online serious game about proteins docking, solve all the levels and share your score!
BioBloxVR is a visualization tool for the docking of proteins using virtual reality. It is still under development, if you want to have a try contact us!
BioBlox is an interactive platform combining: 3D, 2D and 1D visualisations, interactions, audio feedback (sonification). It is also being designed to become a puzzle gaming which can be played solo or in teams, where for example each team-member controls one molecule (target or candidate for docking).
We address the docking of molecules onto a given target molecule (typically a protein). Such a molecular target offers a complex 3D form with many pockets, holes and textured regions — imagine a moon-like surface wrapped around a 3D folded ribbon—on its bounding surface where other (usually much smaller) molecules can come by and bind to. The process is dynamic in that each such molecule has a bounding form which slightly deforms upon interactions and under the constant bombardment of tiny water molecules (in vivo simulation). This problem is key to the understanding of all cellular processes and in particular to the practical application of drug design.
Crowd sourcing of complex scientific problem is still in its infancy, but is gaining grounds and approval by the scientific communities. Early examples include SETI@home (search for extra terrestrial life) and GalaxyZoo (classification of galaxies). More recent and directly relevant projects are FoldIt and EteRNA: on-line scientific puzzle-solving games about folding proteins and RNA.
The BioBlox project is supported by the BBSRC
September 2017: BioBloxVR on show at the next New Scientist Live, ExCeL London : live.newscientist.com (Sept. 28 - Oct. 1).
May 2017: BioBlox suite of games (2D, 3D, VR) at the annual Imperial Festival (May 6-7).
February 2017: BioBlox suite of games (2D, 3D, VR) at the annual Schroedinger lecture, Imperial College London (Feb. 1st).
December 2016: First version of BioBlox3D in VR shown at the Develop VR day in London.
October 2016: BioBlox 2D and 3D to be shown at the Imperial Global Challenge Showcase (27-28 Imperial College White City Campus). Tickets and show information here.
September 2016: both the 2D (first time) and 3D versions of BioBlox to be shown at the New Scientist Live event (London ExCeL, September 22-25).
July 2016: BioBlox was shown at Develop, the annual UK games industry main meeting (Brighton, July 12-14).
May 2016: BioBlox was shown at the Imperial Festival (May 7-8, Imperial College London).
March 2016: BioBlox was shown at the 7th VizBi meeting (EMBL, in Heidelberg, Germany March 9-11).
December 2015: BioBlox was shown at BiVi 2015, the 2nd annual UK meeting of the Bio-Visualisation Community (Dec. 2-3, the Genome Analysis Centre, Norwich).
September 2015: Fringe event on the theme of Designs for Life (Sept. 24, Imperial College London)
20 June 2017: Press Release
The BioBlox group consists of two teams, one based @ the Dept. of Life Sciences @ Imperial College London and one based @ the Dept. of Computing @ Goldsmiths College, also in London, UK. These two teams have worked together since 2007 on various projects, including the History of the Species (SIGGRAPH 2007) and FoldSynth (BioVis 2011). Joining them are Experts and Games Industry & Technology Partners.